UQCRC2 ubiquinol-cytochrome c reductase core protein II [ Homo sapiens (human) ]
Gene ID: 7385, updated on 2-Apr-2017
Official Symbol
UQCRC2provided by HGNC
Official Full Name
ubiquinol-cytochrome c reductase core protein IIprovided by HGNC
Primary source
HGNC:HGNC:12586
Ensembl:ENSG00000140740 MIM:191329; VegaTTHUMG00000131585
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
QCR2; UQCR2; MC3DN5
Summary
The protein encoded by this gene is located in the mitochondrion, where it is part of the ubiquinol-cytochrome c reductase complex (also known as complex III). This complex constitutes a part of the mitochondrial respiratory chain. Defects in this gene are a cause of mitochondrial complex III deficiency nuclear type 5. [provided by RefSeq, Jul 2015]