Yep, it is extremely easy to use! Took me a long time to get all set up since I torrented/downloaded it and everything else needed for it to work, but once I got it working it worked brilliantly without any problems. I was expecting it to take me to lag hell and make everything run super slow since it is a massive program, but it didnt do that at all! I even ran another massive game on top of that (I was using it to play Maplestory) and it still worked amazingly with little to no lag. So Sims 4 should definitely run smoothly.
All you gotta do to get it going is click the file and wait for the virtual screen to start up, and from there you just use it like a normal computer. You can also continue to do whatever on your mac since the whole virtual PC screen is in its own window.